Veozah (fezolinetant) is a non-hormonal prescription medication approved by the FDA in May 2023 to treat moderate to severe vasomotor symptoms (VMS) associated with menopause, such as hot flashes and night sweats. Unlike hormone replacement therapy (HRT), Veozah works by blocking neurokinin B (NKB) receptors in the brain's hypothalamus, helping regulate body temperature without introducing hormones. This makes it a popular option for women who cannot or prefer not to use HRT due to risks like breast cancer history or other contraindications.
In this comprehensive Veozah reviews guide, we'll explore real user experiences, average ratings from trusted platforms, common side effects, how it works, and expert insights. Based on aggregated data from patient reviews and clinical studies, Veozah has shown promising results for many, but individual outcomes vary. Always consult a healthcare provider before starting any medication, as this information is for educational purposes and not a substitute for professional medical advice.
How Veozah Works: A Quick Overview
During menopause, declining estrogen levels can make the body more sensitive to NKB, leading to hot flashes and night sweats in about 75-80% of women. Veozah, taken as a 45mg oral tablet once daily, blocks NKB receptors to reduce these symptoms. Clinical trials, such as the SKYLIGHT studies, demonstrated a reduction in hot flash frequency by over 50% within 12 weeks, with improvements in sleep and quality of life often noticeable as early as week 1.
Key benefits from studies:
-
Reduced hot flashes from an average of 10-12 per day to 4-4.5 per day.
-
Sustained effects over 52 weeks.
-
Hormone-free, making it suitable for those avoiding estrogen-based treatments.
However, Veozah is not for vaginal symptoms or other menopause issues like mood changes or bone loss. It's contraindicated in people with severe liver or kidney problems, cirrhosis, or those taking CYP1A2 inhibitors (e.g., certain antibiotics or antidepressants).
Veozah Reviews: Average Ratings and User Experiences
Based on thousands of Veozah reviews across platforms like Drugs.com, WebMD, Sermo, and GoodRx, the medication earns an average rating of 6.5-7.7 out of 10. About 54-60% of users report positive experiences, citing life-changing relief from hot flashes, while 7-15% note negative effects like side effects or reduced efficacy over time. Here's a breakdown:
Positive Veozah Reviews
Many users praise Veozah for quick, dramatic relief:
-
"Within the first week, my hot flashes stopped completely. It's a miracle pill!" (Rating: 10/10, Drugs.com user, taken for 1-6 months).
-
"Life-changing! No more night sweats after years of suffering. Sleep improved, and no side effects." (Rating: 10/10, WebMD reviewer, post-breast cancer survivor).
-
"Hot flashes reduced by 70% in days. Worth the cost for better quality of life." (Rating: 10/10, GoodRx user).
Common themes: Fast onset (often within 1-4 weeks), better sleep, and hormone-free appeal. Women with breast cancer history or those unable to use HRT often highlight it as a "game-changer."
Negative Veozah Reviews
Some report side effects or waning effectiveness:
-
"Worked great at first, but hot flashes returned after 6 months. Disappointed." (Rating: 5/10, Drugs.com user, taken for 6-12 months).
-
"Severe stomach pain and insomnia. Had to stop after a month." (Rating: 2/10, WebMD reviewer).
-
"No relief after 2 months, plus back pain. Waste of money without insurance coverage." (Rating: 1/10, Sermo patient insight).
Common complaints: Initial side effects like nausea or headaches, reduced efficacy over time (possibly due to tolerance), and high cost ($470-$677 for 30 tablets without discounts).
Mixed Veozah Reviews
-
"Hot flashes lessened but not gone. Mild diarrhea, but manageable. Liver tests fine." (Rating: 7/10, GoodRx user).
-
"Effective for day flashes, but night sweats persist. Better than nothing." (Rating: 6/10, Drugs.com reviewer).
Overall, 81% of clinical trial participants were White, with limited diversity data, but real-world reviews from diverse groups (e.g., Black and Hispanic women, who may experience longer symptoms) show similar trends.
Common Side Effects and Risks in Veozah Reviews
From Veozah reviews and FDA data, side effects are generally mild but can be bothersome. The most reported include:
-
Abdominal pain (common in 10-15% of users).
-
Diarrhea (often temporary; manage with bland foods and hydration).
-
Insomnia or trouble sleeping.
-
Back pain.
-
Hot flashes (ironically, as a rebound or initial effect).
-
Headaches and nausea (subsiding after 1-2 weeks for many).
Serious risks mentioned in reviews:
-
Elevated liver enzymes: Requires blood tests before starting and at months 1-3, 6, and 9. Symptoms like jaundice or fatigue prompt immediate stoppage.
-
Allergic reactions: Rare, but include rash or swelling.
-
No weight gain/loss reported in studies, though some users note appetite changes.
Tips from reviewers: Take at the same time daily, limit caffeine (it can amplify effects), and monitor triggers like alcohol or spicy foods.
Pros and Cons Based on Veozah Reviews
Pros:
-
Hormone-free alternative to HRT.
-
Rapid relief for hot flashes (50-60% reduction).
-
Improves sleep and daily life for most.
-
Once-daily tablet, easy to use.
-
Savings programs available (e.g., $30/month copay card for eligible insured patients).
Cons:
-
High cost without insurance; not always covered.
-
Potential side effects like GI issues or headaches.
-
May lose effectiveness over time for some.
-
Requires regular liver monitoring.
-
Not for all menopause symptoms (e.g., no help for vaginal dryness).
Expert Insights and Alternatives
Board-certified OBGYNs like Dr. Jen Ashton emphasize that Veozah addresses a gap for non-hormonal options, especially for those with cancer risks. Physician ratings on platforms like Sermo give it 3.6-4.0/5 for efficacy and safety, noting good tolerability but access barriers due to cost.
Alternatives if Veozah isn't right:
-
HRT (e.g., estradiol patches) for broader symptom relief.
-
Antidepressants like paroxetine (off-label for hot flashes).
-
Lifestyle changes: Yoga, acupuncture, or avoiding triggers.
-
Other non-hormonal meds: Gabapentin or clonidine.
Discuss with your doctor; Veozah is available via prescription at retail pharmacies.
Frequently Asked Questions About Veozah Reviews
Does Veozah cause weight gain?
No, studies and reviews show no link to weight changes. Menopause itself can cause gradual gain due to hormonal shifts.
How long does Veozah take to work?
Many notice improvements in 1-4 weeks, with full effects by week 12.
Is Veozah safe long-term?
Sustained in 52-week trials, but monitor liver function. Stop if side effects worsen.
What's the cost of Veozah?
Around $470-$677 for 30 tablets; copay assistance can reduce to $30/month for eligible patients.
Veozah reviews highlight its potential as a breakthrough for menopause relief, but results vary. If you're experiencing hot flashes, consult a healthcare professional to see if it's suitable. This content is based on reliable sources and user data as of September 2025.
Sources
-
Veozah oral Reviews and User Ratings: Effectiveness, Ease of Use, and Satisfaction
-
Veozah (Fezolinetant): Uses, Side Effects, Reviews & More - GoodRx
-
Veozah: a new non-hormonal treatment for menopause hot flushes
-
Veozah oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD
Also Read